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AML/MDS

2
Pipeline Programs
3
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

RNA Therapeutic
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Flamingo Therapeutics
Flamingo TherapeuticsBelgium - Leuven
1 program
1
DanvatirsenPhase 1RNA Therapeutic1 trial
Active Trials
NCT05986240Recruiting38Est. Mar 2030
Newave Pharmaceutical
Newave PharmaceuticalCA - Pleasanton
1 program
1
LP-108Phase 11 trial
Active Trials
NCT04139434Completed32Est. Dec 2025
Senti Biosciences
Senti BiosciencesCA - South SF
1 program
SENTI-202PHASE_11 trial
Active Trials
NCT06325748Active Not Recruiting21Est. Aug 2040

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Flamingo TherapeuticsDanvatirsen
Senti BiosciencesSENTI-202
Newave PharmaceuticalLP-108

Clinical Trials (3)

Total enrollment: 91 patients across 3 trials

Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML

Start: May 2024Est. completion: Mar 203038 patients
Phase 1Recruiting

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

Start: Apr 2024Est. completion: Aug 204021 patients
Phase 1Active Not Recruiting

Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML

Start: Jul 2020Est. completion: Dec 202532 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 91 patients
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.