Ametropia

1
Pipeline Programs
3
Companies
14
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Alcon
AlconFORT WORTH, TX
4 programs
1
soft contact lensPhase 41 trial
Alcon Opti-Free® RepleniSH® with Supraclens®N/A1 trial
Lehfilcon A spherical contact lensesN/A1 trial
Serafilcon A toric contact lensesN/A1 trial
Active Trials
NCT00754338CompletedEst. Sep 2008
NCT06408649Terminated129Est. Apr 2025
NCT05959200CompletedEst. Oct 2023
+1 more trials
Bausch + Lomb
Bausch + LombNJ - Bridgewater
3 programs
Purevision Lenses with ReNu MultiplusN/A1 trial
SUPRACOR RegularN/A1 trial
Transepithelial Photorefractive keratectomyN/A1 trial
Active Trials
NCT00722891Completed30Est. Sep 2009
NCT04617080Completed60Est. Feb 2024
NCT04698174Completed39Est. Mar 2022
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
3 programs
alphafilcon A toricN/A1 trial
senofilcon A contact lensesN/A5 trials
senofilcon A toricN/A1 trial
Active Trials
NCT00630305Completed37Est. Jul 2008
NCT06161012Completed67Est. Feb 2024
NCT05361304Completed123Est. Jul 2022
+4 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Alconsoft contact lens
AlconLehfilcon A spherical contact lenses
Johnson & Johnsonsenofilcon A contact lenses
AlconSerafilcon A toric contact lenses
Johnson & Johnsonsenofilcon A contact lenses
Bausch + LombTransepithelial Photorefractive keratectomy
Johnson & Johnsonsenofilcon A contact lenses
Bausch + LombSUPRACOR Regular
Johnson & Johnsonsenofilcon A contact lenses
Johnson & Johnsonsenofilcon A contact lenses
Bausch + LombPurevision Lenses with ReNu Multiplus
Johnson & Johnsonsenofilcon A toric
Johnson & Johnsonalphafilcon A toric
AlconAlcon Opti-Free® RepleniSH® with Supraclens®

Clinical Trials (14)

Total enrollment: 1,014 patients across 14 trials

NCT00349063Alconsoft contact lens

Contact Lens Wettability

Start: Jul 2005
Phase 4Completed
NCT06408649AlconLehfilcon A spherical contact lenses

Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)

Start: Nov 2024Est. completion: Apr 2025129 patients
N/ATerminated
NCT06161012Johnson & Johnsonsenofilcon A contact lenses

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over Two Weeks of Wear

Start: Nov 2023Est. completion: Feb 202467 patients
N/ACompleted
NCT05959200AlconSerafilcon A toric contact lenses

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses

Start: Aug 2023Est. completion: Oct 2023
N/ACompleted
NCT05361304Johnson & Johnsonsenofilcon A contact lenses

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.

Start: May 2022Est. completion: Jul 2022123 patients
N/ACompleted
NCT04698174Bausch + LombTransepithelial Photorefractive keratectomy

Safety and Efficacy of a New Transepithelial Photorefractive Keratectomy Treatment

Start: Feb 2021Est. completion: Mar 202239 patients
N/ACompleted
NCT04531241Johnson & Johnsonsenofilcon A contact lenses

Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology

Start: Aug 2020Est. completion: Sep 2020136 patients
N/ACompleted
NCT04617080Bausch + LombSUPRACOR Regular

Safety and Efficacy of Different Add Powers With a New Presbyopic Lasik Treatment Algorithm

Start: Jan 2020Est. completion: Feb 202460 patients
N/ACompleted
NCT03319212Johnson & Johnsonsenofilcon A contact lenses

Clinical Characterization of Symptomatic Populations

Start: Sep 2017Est. completion: Aug 2018105 patients
N/ACompleted
NCT01990664Johnson & Johnsonsenofilcon A contact lenses

Clinical Evaluation of Lapsed Contact Lens Wearers Who Are Re-fit Into Senofilcon A Contact Lenses

Start: Nov 2013Est. completion: Apr 2014199 patients
N/ACompleted
NCT00722891Bausch + LombPurevision Lenses with ReNu Multiplus

Ocular Responses to Short and Long-term Lens Wear

Start: Jul 2008Est. completion: Sep 200930 patients
N/ACompleted

Comparison of Two Toric Contact Lenses on Current Toric Wearers

Start: Feb 2008Est. completion: Jun 200889 patients
N/ACompleted
NCT00630305Johnson & Johnsonalphafilcon A toric

Endothelial Bleb Response With Toric Lenses

Start: Jan 2008Est. completion: Jul 200837 patients
N/ACompleted
NCT00754338AlconAlcon Opti-Free® RepleniSH® with Supraclens®

Evaluation of Disinfecting Solutions and Protein Remover With a Silicone Hydrogel Lens

Start: Jan 2008Est. completion: Sep 2008
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space