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Allergic Rhinoconjunctivitis

7
Pipeline Programs
11
Companies
10
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
2
3
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
2100%
+ 10 programs with unclassified modality

Competitive Landscape

11 companies ranked by most advanced pipeline stage

Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
Grastek®Phase 4
MSD
MSDIreland - Ballydine
1 program
1
Grastek®Phase 41 trial
Active Trials
NCT02394600Completed93Est. Jun 2016
Allergopharma
AllergopharmaGermany - Reinbek
1 program
1
NovoHelisen DepotPhase 41 trial
Active Trials
NCT06778213Recruiting67Est. Dec 2026
Sandoz
SandozAustria - Kundl
1 program
1
Depiquick BirchPhase 31 trial
Active Trials
NCT01902992Completed202Est. Jul 2012
Inmunotek
InmunotekSpain - Madrid
1 program
1
MM09-MG01Phase 31 trial
Active Trials
NCT04874714Terminated18Est. Oct 2023
Immunomic Therapeutics
2 programs
2
CryJ2-DNA-LAMP plasmid vaccine by intramuscular injectionPhase 1Vaccine1 trial
CryJ2-DNA-LAMP plasmid vaccine by intramuscular injectionPhase 1Vaccine1 trial
Active Trials
NCT01707069Completed24Est. Jun 2013
NCT01966224Completed17Est. Dec 2013
Lundbeck
LundbeckDenmark - Copenhagen
1 program
Alutard phleum pratense subcutaneous immunotherapyN/A1 trial
Active Trials
NCT01085526Completed30Est. Sep 2014
Faes Farma
Faes FarmaSpain - Leioa
1 program
BilastinePHASE_1_21 trial
Active Trials
NCT01081574Completed36Est. Jun 2012
Blueprint Medicines
Blueprint MedicinesMA - Cambridge
1 program
BLU-808PHASE_21 trial
Active Trials
NCT06922448Completed21Est. Sep 2025
Regeneron
RegeneronTARRYTOWN, NY
1 program
Dupixent®PHASE_2
Stallergenes Greer
Stallergenes GreerFrance - Antony
1 program
STALORAL® Birch 300 IRPHASE_31 trial
Active Trials
NCT05668390Completed553Est. Aug 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AllergopharmaNovoHelisen Depot
MSDGrastek®
Stallergenes GreerSTALORAL® Birch 300 IR
InmunotekMM09-MG01
SandozDepiquick Birch
Blueprint MedicinesBLU-808
Faes FarmaBilastine
Immunomic TherapeuticsCryJ2-DNA-LAMP plasmid vaccine by intramuscular injection
Immunomic TherapeuticsCryJ2-DNA-LAMP plasmid vaccine by intramuscular injection
LundbeckAlutard phleum pratense subcutaneous immunotherapy

Clinical Trials (10)

Total enrollment: 1,061 patients across 10 trials

NCT06778213AllergopharmaNovoHelisen Depot

Evaluation of the Efficacy of Allergen-specific Immunotherapy Using Assessment in an Allergen Exposure chamber-a Randomized Placebo-controlled Double-blind Study

Start: Nov 2024Est. completion: Dec 202667 patients
Phase 4Recruiting

The Impact of Grass SLIT Treatment on Birch Pollen Induced Allergic Rhinitis - a Pilot Evaluation

Start: Apr 2015Est. completion: Jun 201693 patients
Phase 4Completed
NCT05668390Stallergenes GreerSTALORAL® Birch 300 IR

Safety and Efficacy of STALORAL® Birch 300 IR in a Paediatric Population With Birch Pollen-induced ARC w/o Asthma

Start: Sep 2023Est. completion: Aug 2025553 patients
Phase 3Completed

Efficacy and Safety Evaluation for the Treatment of Asthma and Allergic Rhinitis/Rhinoconjunctivitis

Start: Apr 2021Est. completion: Oct 202318 patients
Phase 3Terminated
NCT01902992SandozDepiquick Birch

Efficacy and Safety of Intraseasonal Specific Immunotherapy With Depiquick® Birch

Start: Mar 2012Est. completion: Jul 2012202 patients
Phase 3Completed

Study of BLU-808 in Allergic Rhinoconjunctivitis

Start: Apr 2025Est. completion: Sep 202521 patients
Phase 2Completed

Pharmacokinetic Study of Bilastine in Children From 2 to < 12 Years of Age With Either Allergic Rhinoconjunctivitis (AR) or Chronic Urticaria (CU)

Start: Jan 2010Est. completion: Jun 201236 patients
Phase 1/2Completed
NCT01966224Immunomic TherapeuticsCryJ2-DNA-LAMP plasmid vaccine by intramuscular injection

A Safety and Immunogenicity Phase IB Study of CryJ2-DNA-Lysosomal Associated Membrane Protein (CryJ2 -DNA-LAMP) Plasmid Assessing the Long Term Safety of Previously Treated Subjects

Start: Sep 2013Est. completion: Dec 201317 patients
Phase 1Completed
NCT01707069Immunomic TherapeuticsCryJ2-DNA-LAMP plasmid vaccine by intramuscular injection

A Safety and Immunogenicity Phase I Study of CryJ2-DNA-Lysosomal Associated Membrane Protein (CryJ2 -DNA-LAMP) Plasmid

Start: Oct 2012Est. completion: Jun 201324 patients
Phase 1Completed
NCT01085526LundbeckAlutard phleum pratense subcutaneous immunotherapy

Changes in Specific Immunoglobulin and Blood Basophil Activity During Subcutaneous Immunotherapy in Allergic Rhinitis

Start: Feb 2010Est. completion: Sep 201430 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
1 actively recruiting trials targeting 1,061 patients
11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.