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Allergic Reactions

6
Pipeline Programs
4
Companies
5
Clinical Trials
1 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
0
0
0
3
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

ARS Pharmaceuticals
NEFFYApproved
epinephrine
ARS Pharmaceuticals
alpha-Adrenergic Agonist [EPC]nasal2024

Competitive Landscape

4 companies ranked by most advanced pipeline stage

ARS Pharmaceuticals
ARS PharmaceuticalsCA - San Diego
2 programs
2
NeffyPhase 41 trial
NEFFY(epinephrine)Phase 4
Active Trials
NCT06834165Recruiting600Est. Jun 2027
Pfizer
PfizerNEW YORK, NY
2 programs
2
Brompheniramine maleatePhase 11 trial
ChlorpheniraminePhase 11 trial
Active Trials
NCT00894634Completed37Est. Apr 2009
NCT00837837Completed36Est. Feb 2009
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
1 program
1
Valortim and selected ComponentsPhase 11 trial
Active Trials
NCT01204866Completed5Est. Sep 2010
Inmunotek
InmunotekSpain - Madrid
1 program
Allergenic ExtractN/A1 trial
Active Trials
NCT07195929Not Yet Recruiting30Est. Jan 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
ARS PharmaceuticalsNeffy
Allergy TherapeuticsValortim and selected Components
PfizerBrompheniramine maleate
PfizerChlorpheniramine
InmunotekAllergenic Extract

Clinical Trials (5)

Total enrollment: 708 patients across 5 trials

NCT06834165ARS PharmaceuticalsNeffy

Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy

Start: May 2025Est. completion: Jun 2027600 patients
Phase 4Recruiting
NCT01204866Allergy TherapeuticsValortim and selected Components

Study of Valortim® (MDX-1303) and Its Selected Formulation Components Percutaneous Use

Start: Jul 2010Est. completion: Sep 20105 patients
Phase 1Completed
NCT00894634PfizerBrompheniramine maleate

Study Evaluating Brompheniramine Maleate Liquid in Children and Adolescents

Start: Mar 2009Est. completion: Apr 200937 patients
Phase 1Completed
NCT00837837PfizerChlorpheniramine

Study Evaluating Chlorpheniramine Maleate Liquid in Children and Adolescents

Start: Dec 2008Est. completion: Feb 200936 patients
Phase 1Completed
NCT07195929InmunotekAllergenic Extract

Determination of Blomia Tropicalis Allergen Extract in Prick Test Units

Start: Nov 2025Est. completion: Jan 202730 patients
N/ANot Yet Recruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 708 patients
4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.