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Acute Intermittent Porphyria

2
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
1
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Chiesi
ChiesiBrazil - Santana de Parnaíba
1 program
1
recombinant human porphobilinogen deaminasePhase 2/31 trial
Active Trials
NCT00418795Completed36Est. Jun 2006
uniQure
uniQureNetherlands - Amsterdam
1 program
1
rAAV2/5-PBGD vector dosage 1Phase 11 trial
Active Trials
NCT02082860Completed8Est. Nov 2014

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Chiesirecombinant human porphobilinogen deaminase
uniQurerAAV2/5-PBGD vector dosage 1

Clinical Trials (2)

Total enrollment: 44 patients across 2 trials

NCT00418795Chiesirecombinant human porphobilinogen deaminase

Porphozym in the Treatment of Acute Attacks in AIP

Start: Jun 2003Est. completion: Jun 200636 patients
Phase 2/3Completed
NCT02082860uniQurerAAV2/5-PBGD vector dosage 1

Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria

Start: Nov 2012Est. completion: Nov 20148 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.