Skip to main content

Achilles Tendinopathy

4
Pipeline Programs
7
Companies
13
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
3
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
3100%
+ 3 programs with unclassified modality

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Zimmer Biomet
Zimmer BiometFL - Jacksonville
1 program
1
PRP Injection with eccentric exercisesPhase 41 trial
Active Trials
NCT00761423Completed81Est. Aug 2009
MSD
MSDIreland - Ballydine
1 program
1
etoricoxibPhase 4Small Molecule
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
etoricoxibPhase 4Small Molecule
Sandoz
SandozAustria - Kundl
1 program
1
NGI226Phase 21 trial
Active Trials
NCT05592990Completed45Est. Feb 2026
Bioiberica
BioibericaSpain - Barcelona
1 program
TendoactiveN/A1 trial
Active Trials
NCT01691716Completed100Est. Sep 2013
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
etoricoxibPHASE_4Small Molecule5 trials
Active Trials
NCT01979510Withdrawn0Est. May 2014
NCT01246362Completed65Est. Jan 2014
NCT01229774Completed100Est. Aug 2014
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Merck & Co.etoricoxib
Merck & Co.etoricoxib
Merck & Co.etoricoxib
Merck & Co.etoricoxib
Zimmer BiometPRP Injection with eccentric exercises
Merck & Co.etoricoxib
Merck & Co.etoricoxib
Merck & Co.etoricoxib
Merck & Co.etoricoxib
Merck & Co.etoricoxib
SandozNGI226
Merck & Co.etoricoxib
BioibericaTendoactive

Clinical Trials (13)

Total enrollment: 808 patients across 13 trials

Efficacy of Etoricoxib 60 mg in Modifying Pain Hypersensitivity in People With Knee Osteoarthritis

Start: Aug 2010Est. completion: Dec 201180 patients
Phase 4Completed

Etoricoxib in Acute Ankle Ligament Sprains

Start: Nov 2009Est. completion: Jul 20110
Phase 4Withdrawn

"NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes"

Start: Aug 2009Est. completion: Feb 201256 patients
Phase 4Completed

Efficacy and Safety of Etoricoxib in Acute Ankle Sprain: A Double-Blind Comparative Study Among 2 Treatments Protocols

Start: Dec 2008Est. completion: Sep 200950 patients
Phase 4Unknown
NCT00761423Zimmer BiometPRP Injection with eccentric exercises

The Value of Platelet-Rich Plasma in Chronic Midportion Achilles Tendinopathy: a Double-blind Randomized Clinical Trial

Start: Aug 2008Est. completion: Aug 200981 patients
Phase 4Completed

Pain Post Abdominal Laparoscopy Prevention With Arcoxia

Start: Apr 2006Est. completion: Dec 200660 patients
Phase 4Completed

Safety and Efficacy Study of an Etoricoxib and Tizanidine Fixed Dose Combination in Participants With Moderate to Severe Acute Low Back Pain (MK-0663B-164)

Start: Nov 2013Est. completion: May 20140
Phase 3Withdrawn

Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty

Start: Feb 2011Est. completion: Aug 2014100 patients
Phase 3Completed

Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder

Start: Nov 2009Est. completion: Dec 201045 patients
Phase 3Terminated

Etoricoxib for Routine Post-operative Pain Prophylaxis in Laparoscopic Surgery

Start: Mar 2006Est. completion: Mar 2007126 patients
Phase 3Completed

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

Start: Jun 2023Est. completion: Feb 202645 patients
Phase 2Completed

Efficacy Study of Pre-emptive Etoricoxib for Postoperative Pain and Functional Outcome in Total Knee Arthroplasty

Start: Jul 2011Est. completion: Jan 201465 patients
Phase 2Completed

The Efficacy of Tendoactive, Eccentric Training, and the Combination of Both as a Treatment of Achilles Tendinopathy

Start: Apr 2012Est. completion: Sep 2013100 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.